What Can Cause A High Psa Besides Cancer

what can cause a high psa besides cancer

What Can Cause a High PSA Besides Cancer?

PSA levels are often considered normal if they do not exceed four ng/mL. However, these numbers can fluctuate over time, even in the blood of the same man. Moreover, men with a PSA level above four ng/mL have been found to be free of cancer. Here are some reasons why a high PSA level may not necessarily be a sign of prostate cancer.

Urinary Tract Infection (UTI)

PSA is produced by the prostate gland and may indicate prostate or urinary tract issues. High PSA levels can be caused by a variety of health conditions. Inflammation of the prostate or urinary tract can increase PSA levels, and these symptoms can include pain during urination, blood in the urine, and inability to urinate. A urinary tract infection can also be caused by a surgical procedure, including insertion of a scope into the bladder.

Symptoms of a UTI can raise PSA levels, and it can be difficult to distinguish between the two. BPH, which is a chronic inflammation of the prostate, is often undiagnosed and may not require treatment unless it is affecting a person’s quality of life. In such cases, a prostate biopsy should be done to confirm the diagnosis. In the meantime, an enlarged prostate can raise PSA levels, and a doctor may recommend a surgical procedure.

In addition to prostate cancer, other conditions that can raise PSA levels include prostatitis, bacterial infections, or kidney stones. An elevated PSA level should prompt a doctor to examine the urinary tract. Among other things, it is important to understand how the PSA test works. Although it cannot rule out the presence of prostate cancer, it is an excellent way to determine your risk for the condition.

If you notice elevated PSA levels, your doctor may suspect prostate cancer. Urinary tract infections are the most common cause of elevated PSA. But other conditions may also cause elevated PSA levels. If your PSA is consistently high, your doctor will likely refer you for further testing. And remember that infections can cause high PSA levels, as well. The only way to know for sure is to schedule an appointment with a urologist to ensure that you have a diagnosis.

A urinary tract infection can also be caused by prostate enlargement. Prostate enlargement narrows the urethra, which passes through the prostate gland. Because of the pressure, insufficient emptying of the bladder creates an environment that enables bacteria to multiply rapidly. This condition can eventually lead to bladder infection and even cancer. The risk of prostate cancer is increased by frequent bladder infections.


A high PSA is not always associated with cancer. In fact, trauma can increase the PSA level in the body. According to lead study researcher James Eastham, MD of Memorial Sloan-Kettering Cancer Center, an elevated PSA level is often accompanied by one of three common responses by physicians:

Recent trauma may also raise PSA levels, such as a catheter or prostatitis. However, if you suspect an infection, further evaluation will be required to determine whether a urinary tract infection caused the elevated PSA. If it is, treatment will depend on the type of infection. Also, an enlarged prostate can cause elevated PSA levels, although not all of them are cancerous.

Other risk factors that can elevate PSA levels include age, gender, ethnicity, and smoking. Smoking was associated with lower PSA levels in the US and European groups. Interestingly, the US-EA group was the only ethnic group with a statistically significant difference between PSA levels. Compared with US-EA and NZ-European cohorts, the TW1 group had higher PSA levels than the other three groups. Further, the TW1 cohort carried the highest proportion of high-risk cases.

The PSA level and age at diagnosis were significant factors in the study. The AA and Physicians’ Health Study controls were not associated with PSA, and their median PSA level was 0.83 ng/ml49. These findings suggest that PSA levels can be elevated despite a healthy lifestyle. The authors concluded that trauma can be an additional cause of high PSA levels besides cancer.

Herbal mixtures

Despite its reputation, there is no evidence that herbal mixtures can cause a high PSA level. The most commonly used herbal mixtures, such as pomegranate juice extract (POMx), fail to reduce PSA concentrations. A recent study conducted by Swiss researchers failed to find any statistical difference between men who received pomegranate extract and placebos.

Men who are younger than 40 and with no family history of prostate cancer are generally considered to have low PSA levels. A PSA level of 2.5 ng/mL is considered healthy for most men, while a PSA level between four and 10 ng/ml indicates a 25% chance of developing prostate cancer. However, PSA levels of over 4.0 ng/mL are cause for concern.

However, some studies have found that individual antioxidant supplements failed to lower PSA concentrations in men with PCa. These studies used multiple antioxidants, including vitamin E and selenium. The combination of antioxidants failed to lower PSA concentrations in men with PCa. Herbal mixtures can cause a high PSA besides cancer by upregulating the production of reactive oxygen species.

Although PSA levels are not a definitive indicator of the presence of prostate cancer, they can help doctors detect the disease early. Moreover, a high PSA level can be caused by a wide variety of benign conditions. For example, chronic infections, diabetes, and obesity can all increase PSA levels. Further, prostate inflammation and insulin levels can affect PSA concentrations. Soy is also rich in daidzein and genistein.


PSA levels typically increase with age, but this does not mean that your PSA levels are indicative of prostate cancer. In fact, PSA levels can also be elevated by benign prostatic hyperplasia (BPH), a condition where the prostate gland becomes enlarged or inflamed. These conditions may cause elevated PSA levels and are often accompanied by symptoms similar to cancer.

A man’s PSA level may also be high due to benign prostatic hyperplasia, or BPH. This condition is not cancerous but causes the prostate gland to produce more PSA than it should. BPH is a common problem among men over 50. The good news is that BPH often does not require treatment unless it results in frequent urination. However, if PSA levels are consistently high, it may be a sign of cancer.

While there are many reasons why PSA levels are high, age and ethnicity are the most common reasons for an elevated PSA level. The lead researcher of the study, James Eastham, MD, of Memorial Sloan-Kettering Cancer Center in New York, suggests that aging could also cause high PSA levels. Men in their 70s are more likely to have PSA levels, indicating that their risk of cancer is higher than others.

PSA is an antigen that is produced by healthy prostate cells. The amount of PSA increases as a person ages. Other causes of high PSA levels may include an infection or an enlarged prostate. A doctor can recommend treatment for an infection and wait until the infection is gone before assessing PSA levels. It is also important to know what triggers an elevated PSA level and how to deal with it.

Researchers have found that multi-parametric magnetic resonance imaging is more accurate than needle biopsy in detecting prostate cancer. With MP-MRI, doctors would need only biopsy men with suspicious PSA levels. This could potentially solve the problem of overdiagnosis of men with high PSA levels. But there are still many reasons why aging can cause a high PSA level, including other medical conditions.

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